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الأحد، 21 يوليو 2019

Because of the problems of fat burning body .. Studies to produce a drug that addresses obesity within 5 years



Because of the problems of fat burning body .. Studies to produce a drug that addresses obesity within 5 years





LONDON (Reuters) - Overcoming obesity is not simple, such as dieting, exercise, and the metabolism or metabolism that underlies it is poorly understood, and studies are currently being conducted to find a drug that treats obesity, the Daily Mail reported.



Since 1992, scientists at New York University have been studying a protein called Rage, which lives on the surface of fat cells. Stress, including stress from over-eating, and inflammation affect the operation of the protein RAGE, which develops and retains fat without burning. For power.



The report confirmed that there is research to find a drug to prevent the effects of protein "Rage" to help reduce weight, explaining that more than 70% of Americans are overweight or obese, putting them at risk of chronic diseases such as diabetes, heart disease, and death Early, adding that the preparation for obesity is partially hereditary, but many lifestyle factors help in the infection.




The Western diet is certainly a major contributor to the obesity epidemic, where processed foods have been shown to encourage over-eating. In addition, Americans, as well as residents of at least 45 other countries, have lifestyles that do not depend on Movement, not physical activity, but metabolism, weight gain more complex than just eating less, and more movement, this was evident in a study conducted in 2016 on the "big loser" contestants.


After only 6 years of intensive dieting and 6 weeks of exercise, most of the 14 contestants studied had recovered weight, their burning process was slower, and the hormones that made them more hungry than ever had changed.


Now, a follow-up study has shed some light on the scientists' test of RAGE protein, which lives on the surface of mammalian fat cells. Its mission is to maintain our fat stores, so there is plenty when we need it.


Researchers at New York University have found this protein to be a "metabolic brake" to stop our ability to burn those fats for energy.


Dr. Schmidt and a multidisciplinary team followed the RAGE protein pathway in their research and hopes that a drug for obesity will be reached since 1992.



"We have worked hard in this area, and we have been working on this protein for many years now, and we see potentials based on experiments with animals, although animal experiments do not always see the same results on humans.

Dr. Schmidt hopes she will have an obesity medication ready for clinical trials of the first stage, in a small sample of patients, within 5 years.





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